Breast : Adjuvant
Study: BIG2-06
Participation via CTSU
Description: BIG 2-06/N063D/EGF106708, ALTTO: Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation Study - A randomised, multi-centre, open label, phase III study of adjuvant lapatinib, trastuzumab, their sequence and their combination in patients with HER2/ErbB2 positive primary breast cancer
Limited Participants: None
Notes:
Breast : Adjuvant
Study: E5103
Participation via CTSU
Description: A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide Followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer
Limited Participants: None
Notes:
Breast : Adjuvant
Study: MA.17
Faxed Checklist Only
Description: A Phase III Randomized Double Blind Study of Letrozole Versus Placebo in Women With Primary Breast Cancer Completing Five or More Years of Adjuvant Tamoxifen
Limited Participants: None
Notes: All eligible patients enrolled on MA.17 are eligible
for MA.17L and the registrations should be done at
the same time, however enrollment on MA.17L is
not mandatory.
Breast : Adjuvant
Study: N0733
Description: Phase II Trial of Capecitabine and Lapatinib with or without IMC-A12 in Patients with HER2 Positive, Breast Cancer Previously Treated with Trastuzumab and an Anthracycline and/or a Taxane
Limited Participants: None
Notes:
Breast : Metastatic
Study: N0539
Temporarily Closed
Description: Phase II Trial of Fulvestrant and Bevacizumab in Patients with Metastatic Breast Cancer Previously Treated with an Aromatase Inhibitor
Limited Participants: None
Notes:
| .
| CNS : Brain
Study: N0177
Description: A Pilot and Phase II Study of OSI-774 and Temozolomide in Combination with Radiation Therapy in Glioblastoma Multiforme
Limited Participants: MC Arizona MC Jacksonville
Notes:
CNS : Brain
Study: N0272
Description: Phase I/II Trial of Imatinib Mesylate; (Gleevec; STI-571) in Treatment of Recurrent Oligodendroglioma and Mixed Oligoastrocytoma
Limited Participants: None
Notes:
CNS : Brain
Study: N0572
Description: A Phase I/II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma
Limited Participants: None
Notes:
CNS : Brain
Study: N0574
Description: A Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in the Management of Patients with One to Three Cerebral Metastases - pre registration
Limited Participants: None
Notes:
CNS : Brain
Study: N057K
Temporarily Closed
Description: Phase I/II Evaluation of Everolimus (RAD001), Radiation and Temozolomide (TMZ) Followed by Adjuvant Temozolomide and Everolimus in Newly Diagnosed Glioblastoma
Limited Participants: MC Jacksonville
Notes:
CNS : Brain
Study: N0779
Description: Phase II Study of Vorinostat (SAHA) in Combination with Bortezomib (PS-341) in Patients With Recurrent Glioblastoma Multiforme
Limited Participants: None
Notes:
CNS : Other CNS
Study: N027D
Description: A Phase I Study of CCI-779 and Temozolomide in Combination with Radiation Therapy in Glioblastoma Multiforme
Limited Participants: MC JacksonvilleMC Arizona
Notes:
| .
| GI : Carcinoid
Study: S0518
Participation via CTSU
Description: Phase III Prospective Randomized Comparison of Depot Octreotide Plus Interferon Alpha Versus Depot Octreotide Plus Bevacizumab (NSC #704865) in Advanced, Poor Prognosis Carcinoid Patients
Limited Participants: None
Notes:
GI : Colorectal
Study: N0147
Temporarily Closed
Description: A Randomized Phase III Trial of Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225) after Curative Resection for Patients with Stage III Colon Cancer
Limited Participants: None
Notes:
GI : Sm Bowel
Study: N0543
Description: A Phase II Trial of Pharmacogenetic-Based Dosing of Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy for Advanced Small Bowel Adenocarcinoma
Limited Participants: None
Notes:
| .
| GYN : Ovary
Study: MC0261
Faxed Checklist Only
Description: A Phase II Trial of Flavopiridol and Cisplatin in Advanced Epithelial Ovarian and Primary Peritoneal Carcinomas
Limited Participants: None
Notes:
| .
| Hematology : CLL
Study: N0683
Description: A Phase II Study of Sunitinib Malate for Treatment of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Limited Participants: None
Notes:
Hematology : Non Hodgkin'
Study: N038H
Description: A Phase II Study of CCI-779 in Combination with Rituximab in Patients with Relapsed or Refractory Mantle Cell Lymphoma
Limited Participants: None
Notes:
Hematology : Non Hodgkin'
Study: N0682
Description: A Phase II Clinical Trial of Denileukin Diftitox in Combination with Rituximab in Previously Untreated Follicular B-cell Non-Hodgkin's Lymphoma
Limited Participants: None
Notes:
Hematology : Other Hem
Study: E1F05
Faxed Checklist Only
Description: Phase II Study of Rituximab Given in Conjunction with Standard Chemotherapy in Primary Central Nervous System (CNS) Lymphoma
Limited Participants: None
Notes:
| .
| Lung : NSCLC
Study: 0617
Participation via CTSU
Description: A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High-Dose Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel in Patients With Stage IIIA/B Non-Small Cell Lung Cancer
Limited Participants: None
Notes:
Lung : NSCLC
Study: N0321
Description: Phase I/II Study of PS-341 in Combination with Paclitaxel, Carboplatin, and Concurrent Thoracic Radiation Therapy for Non-small Cell Lung Cancer (NSCLC)
Limited Participants: None
Notes:
Lung : NSCLC
Study: N0528
Description: A Randomized Phase II Study of Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Advanced Non-Small Cell Lung Cancer
Limited Participants: None
Notes:
Lung : NSCLC
Study: N0626
Description: A Phase II Randomized Study of Pemetrexed With Sorafenib Versus Pemetrexed Alone as Second-line Therapy in Patients With Advanced Non-Small Cell Lung Cancer
Limited Participants: None
Notes:
Lung : Sm. Cell
Study: N0621
Description: Phase II Study of the c-SRC Inhibitor, AZD0530, After Four Cycles of Cytoreductive Chemotherapy for Patients With Extensive Stage Small Cell Lung Carcinoma
Limited Participants: None
Notes:
Lung : Thoracic
Study: N0623
Description: Phase II Study of GW786034 in Patients with Malignant Pleural Mesothelioma
Limited Participants: None
Notes:
| .
| Melanoma
Study: N0275
Description: Phase II Trial Evaluating Resection Followed by Adjuvant Radiation Therapy (RT) for Patients with Desmoplastic Melanoma
Limited Participants: None
Notes:
Melanoma
Study: N0675
Description: A Phase II Study of Temozolomide and Everolimus (RAD001) Therapy for Metastatic Melanoma
Limited Participants: None
Notes:
Melanoma
Study: N0775
Description: A Randomized Phase II Trial of Temozolomide (TMZ) and Avastin or ABI-007/Carboplatin (CBDCA) and Avastin in Patients with Unresectable Stage IV Malignant Melanoma
Limited Participants: None
Notes:
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |